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L. Zavileyskiy

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Open access Jul 2026

Global Changes in Unproductive Splicing and NMD Efficiency in Tumors

A robust metric derived from splicing quantification in the RNA-seq data to measure NMD efficiency at a sample level is developed and a striking divergence of NMD efficiency in cancers is observed, suggesting that tumors partially erase the NMD signature of their tissue of origin.

L. Zavileyskiy, A. Mironov, D. D. Pervouchine · 0 citations

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