Automated Detection of Sickled Erythrocytes in Peripheral Blood Smear Images Using YOLO-Based Object Detection
Abstract Sickle cell disease (SCD) is characterized by abnormal red blood cell (RBC) morphology that drives hemolysis and microvascular complications, yet manual smear evaluation remains subjective and difficult to standardize in heterogeneous fields. In this work, we present a clinically grounded and reproducible fram...