This lecture summarizes current evidence on the molecular and genetic mechanisms of resistance to HER2targeted breast cancer therapies and places particular emphasis on factors limiting the efficacy of antibody drug conjugates, which are currently a subject of active investigation.
O. Bragina, E. Y. Sitnikova, A. A. Nesynov et al.· Bulletin of Siberian Medicin...· 0 citations
This review synthesizes current data on cellular, molecular, and systemic predictors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors.
E. Tsarenkova, A. Kalinchuk, E. Shmakova et al.· Clinical and Translational O...· 0 citations
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