Lipoprotein(a) [Lp(a)] is a genetically determined, apolipoprotein B-containing lipoprotein that contributes to cardiovascular risk through atherogenic, proinflammatory, and potentially antifibrinolytic mechanisms. Genetic, epidemiological, and mechanistic evidence supports a causal role for elevated Lp(a) in atheroscl...
P. Sabouret, Domenico Mario Giamundo, J. Popiołek-Kalisz et al.· Reviews in cardiovascular me...· 0 citations
Cardiovascular disease is the leading cause of morbidity and mortality in the elderly. Managing cardiovascular risk in this group is uniquely challenging due to physiological changes, multimorbidity, polypharmacy, and frailty, compounded by the under-representation of older adults in clinical trials Recent advances, in...
G. Dacquino, G. Galati, Luca Genovese et al.· European Journal of Preventi...· 0 citations
A consistent, hypothesis-generating signal is identified suggesting that sacubitril/valsartan may reduce CTRCD incidence and favorably influence cardiac imaging parameters in anthracycline-treated patients, at the cost of increased symptomatic hypotension.
M. Camilli, L. Spadafora· European Heart Journal, Supp...· 0 citations
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