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Author

L. Saltis

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Review Aug 2026

Targeting T-cell exhaustion and tumour immune evasion: a review of emerging strategies.

A complementary therapeutic strategy is discussed: engineering T cells for greater durability in the TME through knockout of exhaustion-associated transcription factors, and reprogramming tumour cells with DNA methyltransferase (DNMTi) and histone deacetylase (HDACi) inhibitors to restore immunogenicity.

L. Saltis, Liew Jun Mun · 0 citations

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