Author

L. Loureiro

2 papers indexed here

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Open access Oct 2026

Extensive monolayer formation after transplantation depends on an RPE subpopulation derived from human iPSCs

Summary Loss of retinal pigment epithelium (RPE) in the eye leads to photoreceptor dysfunction, death, and eventually, vision loss. Cell replacement strategies using RPE cells derived in vitro from pluripotent stem cells are currently evaluated as a potential therapeutic strategy. Generation of polarized monolayers rep...

Karen Tessmer, Juliane Hammer, Sylvia J. Gasparini et al. · iScience · 0 citations

Open access Aug 2026

Preclinical evaluation of homodimeric FAPI target modules for UniCAR-mediated targeting of FAP-expressing tumor and stromal cells

This work reports the first homodimeric FAP inhibitor (FAPI)-based TMs that enable efficient adapter CAR T-cell immunotherapy of FAP-positive tumors and shows that simultaneous dual-targeting leads to enhanced UniCAR-mediated cytotoxicity.

Hugo Boutier, Simona Mattiussi, L. R. Loureiro et al. · Oncoimmunology · 1 citation