Author

L. Pini

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Open access Aug 2026

White-matter disconnection shapes distributed cortical spectral dynamics after stroke

Focal brain lesions are thought to induce sleep-like slow-wave activity in perilesional cortex through altered excitation-inhibition balance and structural disconnection, but whether these dynamics extend to remote yet structurally intact regions remain unclear. Here we combined source-reconstructed high-density EEG (1...

Ilaria Mazzonetto, Miriam Celli, L. Pini et al. · bioRxiv · 0 citations

Review Open access Sep 2026

Experience-Dependent Plasticity of Large-Scale Brain Networks in Aging: How Different Training Modalities Shape Neural Connectivity.

Brain regions are organized into large-scale networks through dynamic functional connections that support sensorimotor and cognitive processes across the lifespan. Age-related disruptions of these functional systems are associated with cognitive and motor decline and increased risk of neurocognitive disorders. A growin...

F. Gennaro, L. Pini, Maurizio Corbetta et al. · Ageing Research Reviews · 0 citations

Review Open access Sep 2026

Rethinking tau‐targeted therapy in Alzheimer's disease: Toward a dual biomarker strategy

A dual‐domain framework is proposed in which tau‐targeted therapies are evaluated using complementary measures of aggregated tau burden and biologically defined soluble tau states, and treatment‐induced increases should be considered favorable only when they accompany aggregate reduction and evidence of a less pathogen...

C. Teunissen, L. Pini, B. Imbimbo · Alzheimer's & Dementia · 0 citations