Open access
Sep 2026
Diagnostic yield of cancer predisposition in a nationwide prospective childhood acute leukemia cohort
The utility of whole-genome sequencing (WGS) for detecting childhood leukemia predisposition remains unclear. We perform a nationwide, prospective, population-based study of 181 children with acute leukemia to assess diagnostic yield and clinical utility of a uniformly applied three-pronged strategy, including systemat...
F. Taylan, A. Staffas, Sara Sjögren et al.
· Nature Communications · 0 citations