Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9-23 months in Uganda: a phase 4, single-blind, randomised clinical trial.
BACKGROUND Fractional doses of yellow fever vaccines have been shown to be safe and immunogenic in randomised controlled trials in adults and children. However, little evidence still remains in children younger than 2 years. We assessed immunogenicity of one-fifth (0·1 mL) and one-half (0·25 mL) fractional doses compar...