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Author

L. Manco

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2 papers indexed here

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Mar 2024

Comparing HbS Haplotypes Identified with Different Sets of Single Nucleotide Polymorphisms: An Analysis in a Sample of HbAS and HbSS Individuals from São Tomé e Príncipe

ABSTRACT:Sickle cell anemia occurs in individuals who are homozygous for the sickle hemoglobin (HbS) allele. The haplotypes of the HbS alleles can be traditionally ascertained through the analysis of five to eight informative restriction fragment length polymorphisms within the HBB gene cluster, defining the five major...

L. Manco, Inês Salgado, S. Almeida et al. · 0 citations
Mar 2024

Genetic Ancestry Strongly Impacts MAPT (17q21.31) Haplotype Frequencies of South American Populations

abstract:Genetic and archaeological studies indicate that the American continent has undergone multiple waves of human migration, shaping a complex population genetic structure comprising three major ethnic groups—Native American, European, and African—unevenly distributed across the continent. In this study, we examin...

M. A. Alfonso-Sánchez, J. Dipierri, Ibone Espinosa et al. · 0 citations

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