Author

L. Lazaridis

2 papers indexed here

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Aug 2026

Feasibility of First-line Lomustine-Temozolomide (CCNU/TMZ) in Elderly Patients with MGMT-methylated Glioblastoma: A Multicenter Retrospective Cohort Study

The CeTeG/NOA-09 trial showed improved survival with lomustine (CCNU) plus temozolomide (TMZ) over TMZ alone in O6-methylguanine-DNA-methyltransferase (MGMT) promoter-methylated glioblastoma patients aged 18-70 years. Data on feasibility, tolerability and outcomes in patients over 70 receiving this regimen are la...

Julia Scheuble, T. Zeyen, Matthias Schneider et al. · Neuro-Oncology Practice · 0 citations

Review Open access Sep 2026

Machine learning models for adverse drug reaction prediction. A systematic review and three-level multilevel meta-analysis

Background Adverse drug reactions (ADRs) are a leading cause of preventable hospitalization, yet the dominant pharmacovigilance paradigm remains reactive. Machine learning (ML) offers a data-driven alternative, but the evidence base has not been formally meta-analyzed under clinically realistic inclusion criteria and a...

G. Cappello, C. Oster, T. Schmidt et al. · Frontiers in Pharmacology · 0 citations