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L. Laramée

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Sep 2026

Abstract PR005: Investigating mechanisms of resistance in Philadelphia chromosome-like acute lymphoblastic leukemia

Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is characterized by targetable kinase fusions with different tyrosine kinase inhibitors (TKIs) currently being investigated in clinical trials. While kinase domain (KD) mutations represent the primary mechanism of acquired resistance in Phi...

M. Rozendaal, L. Laramée, Aurélien Choblet et al. · 0 citations

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