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L. Kalinowski

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Open access Oct 2026

Positive Allosteric Modulation of mGlu and Muscarinic Receptors Differentially Regulate Nitric Oxide-Dependent Signaling in a Scopolamine-Induced Model of Cognitive Impairment

Background/Objectives: The aim of the study was to evaluate the effects of positive allosteric modulators (PAMs) of metabotropic glutamate (mGlu2, mGlu5) and muscarinic (M1, M4) receptors on nitric oxide (NO֗)-dependent pathways. Scopolamine-induced cognitive impairment model reflecting cholinergic dysfunction characte...

G. Burnat, Michał Santocki, A. Siekierzycka et al. · 0 citations

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