Rheumatoid arthritis (RA) arises from interactions among immune, stromal, and osteoimmune compartments, supporting interest in agents with multilevel activity, such as celastrol. This narrative review critically integrates evidence on its chemical–pharmacological basis, immunomodulatory mechanisms, cellular effects, an...
F. Corona-Meraz, B. Martín-Márquez, L. E. Cobos-Puc et al.· International Journal of Mol...· 0 citations
Exosomes are small vesicles released by various cell types—compounds of a lipid bilayer and surface proteins that facilitate their recognition, direction, and uptake by the target cell. Inside, exosomes contain proteins, lipids, and nucleic acids, the composition of which varies depending on the cell of origin. Exosome...
Francisco Antonio Guillermo Mateos-Ramírez, L. Hernández-Ortega, C. M. Gurrola-Díaz et al.· International Journal of Mol...· 0 citations
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