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Author

L. Filippi

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Open access Aug 2026

Mapping the Synaptome in Neurodegeneration: Emerging Clinical Applications of SV2A PET Imaging.

Synaptic loss is a core pathological feature of neurodegenerative disorders and closely relates to cognitive and functional decline. Positron emission tomography (PET) targeting synaptic vesicle glycoprotein 2A (SV2A) has recently emerged as a promising tool for the indirect assessment of presynaptic alterations in the...

L. Filippi, S. Nuvoli, A. Spanu et al. · 0 citations
Review Sep 2026

Amyloid-β PET Radioligands in Alzheimer's Disease: From Plaque Detection to Biomarker-Guided Patient Stratification and Therapeutic Monitoring.

A narrative review of the principal Aβ positron emission tomography radioligands and their methodological framework, including visual reads, the standardized uptake value ratio, and the Centiloid scale, which harmonized quantitative output across tracers, scanners, and protocols and may enable cross-site comparison in...

Simone Lista, L. Filippi, Enzo Emanuele et al. · 0 citations

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