Aug 2026
Dual MDM2 and PPARG regulatory axes mediate the antiepileptic effects of Gouteng: An Integration of Bioinformatics, Network Pharmacology, Machine Learning, Molecular Docking, and MD Simulations.
Gouteng exerts antiepileptic effects by targeting and regulating the dual MDM2-MDM4/TP53 and PPARG-NCOA1/RXRA regulatory axes, thereby mediating neuro inflammation inhibition and neuronal protection.
Hong-Quan Zhang, Lin Chen, Xian-Jun Yuan et al.
· Neuropharmacology · 0 citations