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L. Dreher

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Review Oct 2026

Association between elevated lipoprotein (a) and venous thromboembolism: A systematic review and meta-analysis.

BACKGROUND Elevated lipoprotein(a) [Lp(a)] is an established cardiovascular risk factor linked to atherogenesis, inflammation, and thrombosis; however, its association with venous thromboembolism (VTE) remains uncertain, with inconsistent findings across observational studies. AIMS To systematically evaluate the asso...

M. Abdelnabi, C. Puchongmart, Ramzi Ibrahim et al. · 0 citations
Review Open access Sep 2026

Connective tissue disorders and cardiac arrhythmias: genetic pathways, mechanistic bridges, and clinical implications

Recognition of CTDs as both vascular and electrical disorders reframes clinical management and underscores the need for prospective registries and genotype-phenotype studies to refine surveillance and prevention strategies.

L. Dreher, Hussein Abdul Nabi, Ramzi Ibrahim et al. · 0 citations
Review Oct 2026

Ventricular Arrhythmias in Marfan Syndrome: Prevalence and Clinical Correlates in a Multicenter Cohort.

BACKGROUND Ventricular arrhythmias are increasingly recognized in Marfan syndrome, but associated clinical and structural features remain incompletely defined. METHODS We performed a retrospective multicenter cohort study of 783 adults with confirmed Marfan syndrome at 3 Mayo Clinic sites. Clinical, arrhythmic, echoc...

L. Dreher, Hussein Abdul Nabi, C. Kanaan et al. · 0 citations
Open access Jan 2026

The Role of Genetic Variation in Phenotypic Variability in Loeys–Dietz Syndrome

Distinct genotype–phenotype associations exist among LDS subtypes, and TGFBR1 and TGFBR2 variants are associated with a greater burden of aggressive vascular disease, whereas SMAD3 variants are linked to mitral valve disease, peripheral neuropathy, and osteoarthritis.

Hussein Abdul Nabi, L. Dreher, Jack Hartnett et al. · 0 citations

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