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Open access Oct 2026

Association of clinical risk scores with coronary atherosclerotic plaque burden and progression assessed by coronary computed tomography angiography

Atherosclerotic cardiovascular disease (ASCVD) risk scores are widely used to guide preventative therapies and referral of patients for non-invasive imaging, yet lack diagnostic and prognostic precision at the individual level. Coronary computed tomography angiography (CCTA) enables direct visualisation, quantifi...

L. Deres, J. Stewart, Y. Yong et al. · 0 citations
Open access Oct 2026

From obesity and sedentary lifestyle to energetic and metabolic failure: empagliflozin and semaglutide reverse mitochondrial and metabolic dysfunction in experimental HFpEF

HFpEF accounts for nearly half of all heart failure cases and carries substantial morbidity and mortality. Beyond hemodynamic abnormalities, it is now increasingly recognized as a systemic metabolic disorder driven by obesity, insulin resistance, and chronic low-grade inflammation. Mitochondrial dysfunction plays...

S. Tóth, K. Fekete, K. Ordog et al. · 0 citations

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