424. Distinct prefrontal neuronal responses to drug cues and social stimuli following prolonged heroin abstinence
Abstract Background Substance use disorder (SUD), particularly opioid use disorder (OUD), is associated with social impairments that exacerbate relapse risk. The prefrontal cortex (PFC), specifically the prelimbic (PrL) region, regulates both social cognition and drug-seeking behaviors. Clinical and animal studies indi...