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L. C. Onar

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Open access Aug 2026

Integrative Systems Genomics and Pharmacology Define Shared Immune–Vascular Programs and Prioritize an Experimentally Testable Candidate Linking Sleep Loss to Human Atherosclerosis

Background: Sleep loss is epidemiologically linked to atherosclerotic cardiovascular disease, yet shared-transcriptome studies typically intersect differentially expressed gene lists and treat the overlap as a shared response, assuming rather than testing directional agreement. Methods: Controlled human sleep restricti...

L. C. Onar, I. Yilmaz · 0 citations
Open access Jul 2026

An Integrative Transcriptomic, Network Pharmacology, and Molecular Docking Analysis of the Ferroptosis–Fibrosis Axis in Cardiomyopathy with Exploratory Relevance to Diabetic Cardiomyopathy

The findings are consistent with a fibrosis-dominant remodeling signature and suggest potential network-level links between ferroptosis-associated processes and cardiac fibrosis and require validation in independent cohorts and experimental studies.

L. C. Onar, Ersin Guner, I. Yilmaz · 1 citation

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