Author

L. Beck

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Open access Oct 2026

Characterization of an immunodeficiency-associated EZH2 variant

Epigenetic gene regulation is central to the development and function of immune cells. For example, B cell differentiation and function require high levels of EZH2, the catalytic subunit of epigenetic regulator Polycomb Repressive Complex 2 (PRC2). Our clinical evaluation identified two sisters with adult-onset recur...

Francisco J. Pérez-de Los Santos, L. Beck, E. DeCurtis et al. · NAR Molecular Medicine · 0 citations

Open access Jul 2026

Validated Reactive Force Field Quantifies MXene Interfacial Properties, Mechanics, and Thermal Transport

MXenes combine rich surface chemistry, mechanical strength, and high conductivity for a multitude of emerging applications. Predictive modeling supports accelerated materials designs and has been limited by the absence of validated and transferable force fields. Here, we introduce an interpretable, reactive INTERFACE f...

Isaac W. Armstrong, J. Slocik, L. Beck et al. · ACS Nano · 1 citation