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Author

L. A. McDonnell

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Review Open access Sep 2026

CRISPR-based diagnostics as a specificity layer for the early detection of pancreatic cancer.

Although pre-analytical limitations remain to be fully characterized, integrating CRISPR into the diagnostic workflow may contribute to a rapid, cost-effective, and highly specific framework for the early detection of PDAC.

M. A. Rocco, Milda Kirvaitytė, Giulia Lencioni et al. · 0 citations
Jul 2026

Proteomics of Extracellular Vesicles Derived from Primary Cells of Pancreatic Ductal Adenocarcinoma Patients Identifies Ribosomal Proteins Associated with Survival.

It is suggested that the differential loading of translational machinery into the extracellular space─likely via microvesicles or coisolated nonvesicular particles─contributes to poor prognosis, offering new insights into the systemic secretome of aggressive tumors.

Asia Botto, Noa Ndimurwanko, Francesco Finamore et al. · 0 citations

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