Kyra A. Lindley

Abstract B013: Interrogating and modeling progression of early pancreatic intraepithelial neoplasia

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with one of the lowest five-year survival rates of all cancers. Low grade, premalignant pancreatic intraepithelial neoplasias (PanINs) are common in the general population, but despite expression of mutant KRAS, the vast majority of these lesions will n...