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Kyogo Nagashima

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Review Open access Oct 2026

How do low-complexity domain interactions control transcription?

Abstract A substantial portion of the proteome consists of intrinsically disordered regions (IDRs) that do not fold into well-defined structures. IDRs often comprise low-complexity domains (LCDs), whose repetitive, compositionally biased sequences drive multivalent interactions that can lead to liquid–liquid phase sepa...

Jia-Min Guo, Qin-Yu Han, Kyogo Nagashima et al. · 0 citations

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