Author

Kwang-Hee Bae

2 papers indexed here

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Open access Oct 2026

DUSP4 activates adipocyte thermogenesis via CRTC3 dephosphorylation-dependent UCP1 expression.

Obesity arises when a chronic energy surplus overwhelms the storage capacity of adipocytes and subsequently causes systemic metabolic dysfunction. Adaptive thermogenesis, primarily mediated by uncoupling protein 1 (Ucp1) in adipocytes, serves to counteract obesity by dissipating excess energy as heat. Despite extensive...

Min Jeong Son, Hae Un Kook, Jaeeun Jung et al. · Experimental and Molecular M... · 0 citations

Open access Sep 2026

A refined MASH–HCC model identifies macrophage Gadd45b as a key orchestrator of inflammation-driven neoplastic progression

Metabolic dysfunction-associated steatohepatitis (MASH) is emerging as a leading driver of hepatocellular carcinoma (HCC), yet the molecular mechanisms linking metabolic stress, chronic inflammation and tumorigenesis remain poorly understood. Here we established a metabolically relevant, time-efficient MASH-to-HCC mode...

Hyunmi Kim, Gye-Hyeong Kim, H. Yeon et al. · Experimental and Molecular M... · 0 citations