Gain and loss of acquired doxycycline resistance in Lactiplantibacillus plantarum : an adaptive laboratory evolution study
ABSTRACT Probiotics interact in a mutualistic way with humans. Exposure of probiotics to sublethal concentrations of commonly prescribed antibiotics can cause resistance to arise. Over 1,000 generations, we performed an adaptive laboratory evolution experiment to determine if the fitness of the probiotic Lactiplantibac...