Review
Open access
Aug 2026
Senescent immune cells, inflammaging, and bone loss: therapeutic potential and translational challenges of senolytics in osteoporosis
A structured research roadmap is proposed—centered on fate-mapping, lineage-specific depletion, and single-cell multi-omics—to convert the prevailing hypothesis into experimentally testable and clinically actionable evidence, while delineating the translational challenges that must be overcome to achieve precision seno...
Min-Shun Zhu, Jie Zhang, Hou-Shan Fang et al.
· Frontiers in Endocrinology · 0 citations