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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Kunxiang Gong

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2 papers indexed here

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Review Sep 2026

Drug resistance in cancer: Emerging mechanisms, translational barriers, and pharmacological strategies.

Multidrug resistance (MDR) remains a major challenge in cancer treatment. MDR has been explained by single-gene mechanisms, such as overexpression of ATP-binding cassette (ABC) transporters, drug-target mutations, activation of bypass signaling pathways, and increased DNA repair. However, these mechanisms alone are ins...

Xiang Chen, Qin-Guo Huang, Ryan Li et al. · 0 citations
Review Jul 2026

Antibody-Drug Conjugates Against Multidrug-Resistant Cancers: Biomarker-Guided Patient Selection, Payload Engineering, Linker Chemistry, and Bystander Effects.

A comprehensive analysis of the molecular structure of ADCs, the pharmacological principles underlying their potent cytotoxic activity against MDR cancer cells, the genomic and transcriptomic biomarkers that guide ADC patient selection, and the emerging resistance mechanisms that will shape the next generation of promi...

Ryan Li, Xiang Chen, Qin-Guo Huang et al. · 0 citations

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