Clinical trial
Open access
Aug 2026
Rs-fMRI reveals that taVNS improves cognitive and emotional function in mild cognitive impairment by reconfiguration of “sensory relay-salience-default” cross-network effective connectivity: a randomized, double-blind, sham-controlled trial
Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising noninvasive intervention for mild cognitive impairment (MCI), but its clinical efficacy and network-level mechanisms remain unclear. Methods In this prospective, randomized, sham-controlled, parallel-group trial, 60 patients with MCI wer...
Tianjiao Xu, Chun-Lei Guo, Lei Zhang et al.
· Frontiers in Neurology · 0 citations