Review
Open access
Sep 2026
Efficacy and Safety of Switching from Nalfurafine to Difelikefalin in Hemodialysis Patients with Refractory Pruritus
Background: Hemodialysis-associated pruritus is common and can substantially impair quality of life. Given its heterogeneous pathophysiology and variable treatment response, individualized therapeutic strategies are needed. This study investigated the prevalence and severity of pruritus and clinical outcomes after swit...
Yoshimasa Sakurabu, H. Uchida, Kumiko Tokunaga et al.
· Journal of Personalized Medi... · 0 citations