Open access
Jul 2026
Anionic lipids regulate PLCβ membrane recruitment
Phospholipase C-β (PLCβ) enzymes are essential effectors of G protein-coupled receptor signaling that hydrolyze phosphatidylinositol 4,5-bisphosphate (PIP2) at the plasma membrane to generate the second messengers inositol trisphosphate and diacylglycerol. PLCβs play essential roles in diverse physiological processes,...
M. D. Crawford, Marie B. Bennett, Yu Qin et al.
· bioRxiv · 0 citations