Author

Kouhei Tsumoto

3 papers indexed here

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Open access Aug 2026

Photocatalytic proximity labeling for the identification of G-quadruplex DNA-interacting proteins

DNA–protein interactions play an essential role in fundamental cellular biological processes. Herein, we report a photocatalytic proximity labeling approach for the broad screening of G-quadruplex (G4)-interacting proteins (G4IPs) using human telomere G4 DNA modified with a photocatalyst (Ruthenium complex or BODIPY)....

A. Abdelhady, Shinichi Sato, Tatsuki Masuzawa et al. · Communications Chemistry · 1 citation

Open access Sep 2026

Reversible homodimerization of a small leucine-rich proteoglycan PRELP modulates the interactions with TGFβ1 and IGFI-R.

Small leucine-rich proteoglycans (SLRPs) are responsible for various biological functions via their multiple interactions with various proteins. Although some SLRPs form homodimers, it remains unclear how homodimerization affects the molecular functions of SLRPs. Herein, we report the molecular basis and functional sig...

Hirofumi Kosuge, M. Nakakido, Daisuke Kuroda et al. · Journal of Biological Chemis... · 0 citations

Open access Aug 2026

MAXTIA: A high‐throughput platform for rapid functional epitope mapping by kinetic screening of mutant libraries

MAXTIA is presented, a high‐throughput kinetic screening platform that integrates cell‐free protein synthesis with high‐throughput surface plasmon resonance and demonstrates its application to alanine scanning‐based functional epitope mapping, providing a simple and versatile platform for the quantitative analysis of p...

Kihoon Kim, Ryo Matsunaga, T. Yokoo et al. · Protein Science · 0 citations