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Konstantin Khrapko

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Open access Sep 2026

Mitochondria-Associated Transcription Precedes Oxidative Phosphorylation in Human Embryos.

Mitochondria undergo significant structural and functional changes during human pre-implantation embryogenesis, yet the transcriptional activity of both nuclear-encoded mitochondria-associated genes and mitochondrially transcribed genes across this developmental window remains poorly characterized. While mitochondria a...

Andrew J. Piasecki, Melissa Franco, Fausto Capelluto et al. · 0 citations
Open access Jul 2026

Mutational bias shapes protein evolution across RNA viruses

A nearly neutral framework that translates nucleotide mutational spectra into expected amino acid substitution patterns and equilibrium amino acid compositions indicates that departures from the nearly neutral baseline provide a quantitative proxy for purifying and positive selection.

B. Efimenko, Alexander Voronka, Victoriya Skripskaya et al. · 1 citation

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