Author

Koen G. Frenken

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Open access Oct 2026

More pronounced diurnal cortisol rhythms are longitudinally associated with less fatigue in colorectal cancer survivors: A 12-month prospective cohort study.

BACKGROUND Fatigue is amongst the most debilitating cancer-related symptoms, affecting up to one-third of colorectal cancer (CRC) survivors. Accumulating evidence implicates dysregulation of HPA axis as a potential mechanism contributing to chronic fatigue syndrome. We examined longitudinal associations between paramet...

Koen G. Frenken, F. Scheer, J. Qian et al. · Psychoneuroendocrinology · 0 citations

Open access Jul 2026

Sedentary behavior and physical activity are longitudinally associated with diurnal cortisol rhythms in individuals up to 1 year after colorectal cancer treatment: A prospective cohort study

Higher physical activity levels, a larger RA of physical activity, and less sedentary time were associated with more robust diurnal cortisol rhythms, suggesting these behaviors may be targets for interventions aimed at improving cortisol rhythmicity after CRC.

Koen G. Frenken, F. Scheer, J. Qian et al. · Research Square · 0 citations