Author

Kimberly R. Jordan

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Open access Aug 2026

Inhibiting CXCR2 Remodels the Tumor Microenvironment and Blunts Tumor Progression and Dissemination of High-Grade Serous Carcinoma

Abstract High-grade serous carcinoma (HGSC) of the ovary, fallopian tube, and peritoneum has an immunosuppressive tumor immune microenvironment (TIME), mediated in part by infiltrating innate immune cells such as macrophages, neutrophils, and myeloid-derived suppressor cells (MDSC). We hypothesize that manipulating the...

Railey G Mikeska, L. E. Feldman, Elizabeth R. Woodruff et al. · Cancer Research Communicatio... · 0 citations

Open access Sep 2026

Stromal innervation is prognostic in non-muscle-invasive bladder cancer and predicted by a distinct microenvironmental transcriptomic signature

Peripheral nerves are increasingly recognized as active components of the tumor microenvironment (TME). Yet, their role in non-muscle-invasive bladder cancer (NMIBC) and response to Bacillus Calmette-Guérin (BCG) remains poorly defined. Using multispectral imaging, we characterized autonomic and sensory nerve populatio...

Cailin S. Deiter, F. D. de Jong, M. Olislagers et al. · bioRxiv · 0 citations