Preprint
Sep 2026
Multi-Objective Composite Longitudinal Biomarker Scores for Improved Cancer Risk Assessment
Improved Parametric Empirical Bayes (iPEB), which accounts for the intervals between serial measurements, adjusts for covariates, and performs feature selection and optimized biomarker combination, improved lung cancer risk assessment in independent PLCO data, supporting objective-driven optimization of longitudinal bi...
Bitan Sarkar, Ana M. Kenney, James P. Long et al.
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