Cancer immunotherapy faces significant challenges in treating “cold” tumors, which respond poorly to current strategies. Breast cancer is a major cause of cancer-related mortality in women and is a representative immunosuppressive cold tumor. The luminal A subtype of breast cancer exhibits an immune-cold phenotype, wit...
Ulcerative colitis (UC) is a chronic intestinal inflammatory disorder characterized by epithelial barrier disruption, oxidative stress, and gut microbiota dysbiosis. Although epigallocatechin-3-gallate (EGCG) exhibits potent anti-inflammatory and antioxidant activities, its clinical application is limited by poor stabi...
Prabhat Shrestha, Jongjun Park, Seoyeon Jeong et al.· Journal of Controlled Releas...· 0 citations
Results suggest that TMC may serve as a potential therapeutic candidate for targeting hypoxia-associated neuroendocrine signaling and angiogenesis, and demonstrates that TMC acts as a multi-target inhibitor that suppresses hypoxia-driven angiogenic signaling while simultaneously modulating the neuroendocrine stress axi...
S. Hwang, Hye Jung Bang, Seoyeon Jeong et al.· European Journal of Endocrin...· 0 citations
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