AN INTEGRATED MECHANOBIOLOGICAL FRAMEWORK LINKING MECHANICAL LOADING TO TISSUE DEGENERATION IN TEMPOROMANDIBULAR JOINT OSTEOARTHRITIS
Temporomandibular joint osteoarthritis (TMJOA) is a complex degenerative condition involving the coordinated interaction of mechanical loading, cellular mechanotransduction, inflammation, extracellular matrix degradation, and osteochondral remodeling. The traditional concept of TMJOA as a consequence of simple mechanic...