Three-Dimensional Structural Characterization and Spatial Conformational Ensemble Analysis of the Ultra-Large Multivalent Fusion Protein Construct KH-002v003 (2,091 Amino Acid Residues)
Engineering extended macromolecular therapeutics requires comprehensive structural modeling to verify tertiary folding fidelity and domain accessibility across repetitive structural units. In this study, we present the structural characterization of KH-002v003, an ultra-large synthetic multivalent fusion protein constr...