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Author

Khalilah E. Taylor

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2 papers indexed here

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Open access Oct 2026

Folate metabolism in tumor-associated macrophages drives immunosuppressive function to promote tumor growth

Tumor-associated macrophages (TAMs) promote tumor growth, inhibit effector lymphocytes, and induce resistance to immune checkpoint inhibitors (ICI). Therapies designed to deplete TAMs have had little success in the clinic, and strategies aimed to repolarize immunosuppressive TAMs to pro-inflammatory states have struggl...

Matthew P. Zimmerman, Vasyl Zhabotynsky, Hai-Yang Wang et al. · 0 citations
Sep 2026

Abstract A047: Mechanistic dissection and inhibitor targeting of nutrient scavenging in pancreatic cancer

Mutational activation of the KRAS oncogene occurs in over 90% of pancreatic ductal adenocarcinoma (PDAC) patients, and plays a crucial role in tumor initiation, progression, and tumor maintenance. Historically considered undruggable, there has recently been a surge in efforts to develop and improve drugs that target...

Sarah E. Ackermann, Seamus E. Degan, Wen-Hsuan Chang et al. · 0 citations

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