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Author

Khalid Iqbal

2 papers indexed here

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Oct 2026

B-051 Automation of the VeraBIND Tau Plasma Assay to Detect the Seeding Activity of Hyperphosphorylated Tau Before the Onset of Symptomatic Alzheimer’s Disease

Alzheimer’s disease is characterized by neurodegeneration of the brain associated with beta amyloid and tau pathologies. In tau pathology, hyperphosphorylated tau (pTau) binds to normal tau in a prion-like manner forming insoluble tau aggregates. Here, we evaluate the performance characteristics of the recently a...

J. Soldo, K. Shamsundar, Carrie R. Wittmer et al. · 0 citations
Review Open access Aug 2026

Brain organoids in Alzheimer disease and related tauopathies: Challenges and opportunities for translational readiness

This work proposes a ten-metric benchmarking framework and discusses the opportunities and remaining challenges for translational readiness in tauopathy modeling, and identifies three challenges for their translational readiness, maturity, disease-relevant cellular complexity, and pathological accuracy.

A. Guruacharya, Thomas Hartung, Roberta Souza dos Reis et al. · 0 citations

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