Integrative Single-Cell, Spatial, and Bulk Transcriptomics Characterizes an Outcome-Associated, Spatially Organized Mesenchymal Program in IDH-Mutant Glioma
Simple Summary Gliomas are brain tumors that differ widely in how aggressively they behave and in how long patients survive. We asked whether reproducible patterns of gene activity could point to clinically important features of these tumors. By combining data from individual cells, whole-tumor samples, and intact tiss...