Hippocampal transcriptomic profiling reveals interferon, unfolded protein response, and synaptic signatures in RORγt-transgenic mice
Aim RORγt-transgenic mice provide a model of sustained T helper 17-cell bias, but the associated hippocampal transcriptional profile is incompletely characterized. We investigated gene-level and gene-set expression differences in this model. Methods Bilateral hippocampal samples from 10-week-old male RORγt-transgenic m...