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Author

Kensuke Sasaki

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Open access Aug 2026

Magnesium Attenuates Renal Senescence and Fibrosis With Reduced DNA Damage Response and H3K4me3 Enrichment at the p16INK4a Promoter

Renal fibrosis is a final pathway leading to end‐stage renal disease, with cellular senescence contributing to fibrosis and inflammation. Magnesium ions (Mg2+) are implicated in DNA stabilization and epigenetic regulation. In this study, we hypothesized that Mg2+ ameliorates renal fibrosis in association with reduced D...

Makoto Matsubara, Kensuke Sasaki, S. Doi et al. · 0 citations

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