Preprint
Sep 2026
Validity of MMRM-based hypothesis testing under missing-not-at-random mechanisms
In randomized clinical trials with longitudinal continuous outcomes, missing-not-at-random (MNAR) missingness often motivates conservative alternatives to mixed models for repeated measures (MMRM). Such caution is important for estimation, but estimation and testing need not require identical assumptions. Moreover, ove...
K. Maruo, Ryota Ishii, Yusuke Yamaguchi et al.
· 0 citations