Author

Keimpe D. Wierda

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Open access Aug 2026

ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis

Astrocytic polyamine clearance via ATP13A4 tunes extracellular spermidine to shape synapse formation during development, showing how brain extracellular levels are controlled has remained unclear.

S. van Veen, Emily Meeus, D. Irala et al. · Nature Communications · 1 citation

Open access Aug 2026

Developing mouse inhibitory neuron single-cell transcriptomes reveal distinct modes of cell-type diversification

A computational pipeline is developed to enrich and integrate rare cell types across datasets and applied to somatostatin-expressing (SST+) inhibitory neurons, revealing that the developing cortex builds inhibitory diversity through three routes—early commitment, gradual diversification and selective elimination.

Min-Hui Liu, Facundo Ferrero Restelli, Elia Micoli et al. · Nature Neuroscience · 1 citation