Open access
Sep 2026
Sex-specific biological aging clocks across organs and omics.
Sex differentially shapes aging, neurodevelopment and neurodegenerative diseases such as Alzheimer's disease (AD). However, most biological aging clocks (artificial intelligence-predicted age minus chronological age) were trained on sex-pooled samples and implicitly assume sex invariance.Here we developed 38 sex-specif...
Zhi-Yuan Song, Derek Feng, Naowal Azraf Rahman et al.
· Nature Medicine · 0 citations