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Ke-Ru Chen

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Open access Sep 2026

Structural basis of internal Vangl2 peptide recognition by the Dvl2 PDZ domain

Planar cell polarity (PCP) signaling is an evolutionarily conserved pathway that regulates cellular asymmetry and tissue organization during development and homeostasis. Dysregulation of PCP signaling is associated with developmental defects and human diseases, highlighting its essential biological functions. Core PCP...

Han-Mei Yang, Hua-Qing Deng, Ke-Ru Chen et al. · 0 citations

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