Cholangiocarcinoma (CHOL) is a highly heterogeneous and aggressive malignancy that is frequently diagnosed at an advanced stage because of the lack of early biomarkers, resulting in a poor prognosis. Although ANAPC1 overexpression has been reported in other cancers, its role and regulatory mechanisms in CHOL rema...
Ke-Jun Wu, Lei Wang, Yan-Ting Zhan et al.· Hereditas· 0 citations
Cross-sectional analysis of NHANES 2007–2018 cross-sectional data found no overall association between sleep disorders and BC, and Mendelian randomization provided suggestive evidence of a modest association between genetically predicted sleep disorders and ER−, but not ER+, BC.
Si-Yan Chen, Jian-Di Li, Ke-Jun Wu et al.· World Journal of Oncology· 0 citations
In vitro and limited xenograft data indicate that NC restrains CRC growth chiefly through the RAD21–KIF11 axis; KIF11 represents a promising preclinical target, though comprehensive systematic in vivo pharmacodynamic and translational animal validation remains absent in the current study and requires further independen...