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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Ke-Jia Wu

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Open access Oct 2026

Design of readers for pathological PTM proteoforms in Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by heterogeneous Tau phosphorylation and aberrant amyloid-β (Aβ) processing, yet molecular tools that distinguish closely related molecular states of tau and Aβ with predefined specificity remain difficult to develop. Here, we designed de novo protein readers targeting three di...

Ke-Jia Wu, Tiana Schantz, Lemuel Chang et al. · 0 citations
Open access Oct 2026

MYC targeted de novo binders impair tumor growth

MYC is one of the most frequently dysregulated oncogenic drivers across many cancers, yet direct therapeutic targeting has remained difficult because its function is mediated by disordered regions and transient protein-protein interactions. Here we design proteins that bind epitopes within regions of MYC whose sequence...

N. McNamara-Bordewick, Ke-Jia Wu, Yu-Long Su et al. · 0 citations

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